Search and filter the primary research behind Halo's longevity model — what the evidence shows, how strong it is, and where its limits are — with a link to every original study.
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Strong evidence
Moderate evidence
Limited evidence
Evidence quality is graded per record, not for the library as a whole. Each card names the specific reliability or bias concerns that apply — self-report accuracy, reverse causation, confounding — next to the claim they qualify.
These summarise population-level associations. They describe patterns across large groups of people, not a prediction about you specifically.
First-degree relative with colorectal cancer associated with 1.87x risk of colorectal cancer (95% CI 1.68–2.09) in a pooled analysis of 46 studies
Causal status: Associational; shared genetics and environment both contribute
Reliability / bias notes: Colorectal-cancer-specific, not all cancer sites; this pooled estimate does not stratify by the relative's age at diagnosis (the under-60 cutoff used in our question could not be verified against a single landmark source)
Mehraban Far et al · World J Gastroenterol · 2019 · PMID 31435179
Highest vs lowest Omega-3 Index quintile associated with 34% lower risk of death from any cause in the Framingham Offspring Cohort (n=2500, median 7.3-year follow-up)
Causal status: Associational; biologically plausible anti-inflammatory/anti-arrhythmic mechanism, but single cohort, not RCT-confirmed for mortality
Reliability / bias notes: Relatively short follow-up and single baseline measurement; modest sample size and event count (350 deaths)
Harris et al · J Clin Lipidol · 2018 · PMID 29559306