Key finding
~10 mmHg SBP lowering in RCT meta-analysis reduced all-cause mortality RR 0.87; observational 20 mmHg higher usual SBP materially increased vascular mortality
Evidence & causal status
Strongest tier
Strong randomized/interventional evidence
Caveats & limitations
Reliability / bias notes: Treatment status, age, white-coat effect, overtreatment; lower is not always better
This describes a population-level association from published research. It is not a prediction about any one individual, and association is not the same as causation unless stated otherwise above.