Heart Rate Variability — Halo Research Library

Reduced heart rate variability and mortality risk in an elderly cohort. The Framingham Heart Study

Moderate

Heart Rate Variability Observational evidence

Cohort study

1-SD decrement in low-frequency HRV power associated with 1.70x greater all-cause mortality hazard (95% CI 1.37–2.09) over 4 years in an elderly community cohort

Causal status: Associational; reflects autonomic dysfunction, prognostic value shown independent of traditional risk factors

Reliability / bias notes: Older, smaller cohort (n=736, 74 deaths); short 2-hour ECG recording window; results in elderly may not generalize to younger adults

Tsuji et al · Circulation · 1994 · PMID 8044959

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